Development and Validation of a Healthcare Utilization-Based Algorithm to Identify Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Douglas W Mapel,1,* Melissa H Roberts,1,* Susan Sama,2 Priyanka J Bobbili,3 Wendy Y Cheng,3 Mei Sheng Duh,3 Catherine Nguyen,3 Philippe Thompson-Leduc,3 Melissa K Van Dyke,4 Kieran J Rothnie,4 Devi Sundaresan,2 Julia M Certa,5 Thomas S Whiting,5 Jennifer L Brown,5 Douglas W Roblin5 1College of Pharmacy, University of New Mexico, Albuquerque, NM, US

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Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity.

Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases MASS VANILLA with high mortality rates.Here we identify for the first time a multifunctional surface lipoprotein of B.recurrentis, termed HcpA, and demons

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Foundational principles of classical Ayurveda research

Double-blind randomized controlled trials (RCTs) are viewed as the golden standard of drug research ORG VITAMIN C CHERRY SPRAY in Western medicine.However, RCTs are far from "golden" in many respects.They are impractical for many therapies, such as for surgeries and complex lifestyle changes.They encourage a one-size-fits-all approach to medical tr

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Towards Safe Robotic Agricultural Applications: Safe Navigation System Design for a Robotic Grass-Mowing Application through the Risk Management Method

Safe navigation is a key objective for autonomous applications, particularly those involving mobile tasks, to avoid dangerous situations and prevent harm to humans.However, the integration of a risk management process is not yet mandatory in robotics development.Ensuring safety using mobile robots is critical for many real-world applications, espec

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